Since the original description of migraine with brainstem aura, significant advances have been made in the knowledge of migraine aura pathophysiology. Nowadays, typical migraine aura symptoms are thought to be the clinical consequence of a transient cortical dysfunction caused by a cortical spreading depression (CSD) . However, the underlying
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1.4.2 Persistent aura without infarction - ICHD-3. Aura symptoms persisting for one week or more without evidence of infarction on neuroimaging. Persistent aura symptoms are rare but well documented.

Aura is a complex, reversible neurological manifestation that occurs during or before the onset of the headache phase in migraine 1.The third edition of the International Classification of

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    • migraine with brainstem aura symptoms